This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Autologous myoblasts for the treatment of fecal incontinence; results of a phase 2 randomized placebo-controlled study (MIAS). Ann Surg 2018; 267: 443–450.
Published: 17th May 2018
Authors: Boyer O, Bridoux V, Giverne C, Bisson A, Koning E, Leroi A-M et al.
Conclusion
Intrasphincteric injection of myoblasts was safe and well tolerated, and improved faecal incontinence scores at 12 months (but not six months) in this study of 24 patients: score 6.5 versus 15, P=0.006.
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