This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effectiveness of liposomal bupivacaine in colorectal surgery: a pragmatic nonsponsored prospective randomized double blinded trial in a community hospital. Dis Colon Rectum 2016; 59: 862-869.

Published: 30th March 2017

Authors: Knudson R, Dunlavy PW, Franko J, Raman SR, Kraemer SR

Conclusion

Fifty-seven patients were included. Use of liposomal bupivacaine did not reduce postoperative opioid use compared to standard bupivacaine.

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Effect of intravenous acetaminophen on postoperative hypoxemia after abdominal surgery. The FACTOR Randomized Clinical Trial. JAMA 2020; 324: 350-358.

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Efficacy and safety of patient-controlled analgesia compared with epidural analgesia after open hepatic resection. A systematic review and meta-analysis. Ann Surg 2019; 270: 200-208

Authors: Li J, Pourrahmat M-M, Vasilyeva E, Kim P, Osborn J, Wiseman S et al.

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Intravenous patient-controlled analgesia versus thoracic epidural analgesia after open liver surgery. A prospective, randomized, controlled, noninferiority trial. Ann Surg 2019; 270: 193-199

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A 96‐hour continuous wound infiltration with ropivacaine reduces analgesic consumption after liver resection: A randomized, double‐blind, controlled trial. J Surg Oncol 2019; 119: 47-55

Authors: Peres‐Bachelot V, Blanc E, Oussaid N, Perol D, Daunizeau-Walker AL, Pouderoux S et al.

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Conventional epidural vs transversus abdominis plane block with liposomal bupivacaine: a randomized trial in colorectal surgery. J Am Coll Surg 2018; 227: 78–83.

Authors: Torgeson M, Kileny J, Pfeifer C, Narkiewicz L, Obi S

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Preperitoneal or subcutaneous wound catheters as alternative for epidural analgesia in abdominal surgery. A systematic review and meta-analysis. Ann Surg 2019; 269: 252-260.

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Systematic review and meta-analysis of epidural analgesia versus different analgesic regimes following oesophagogastric resection. World J Surg 2018; 42: 204-210.

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Effect of perioperative gabapentin on postoperative pain resolution and opioid cessation in a mixed surgical cohort. A randomized clinical trial. JAMA Surg 2018; 153: 303-311.

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Pain control with continuous infusion preperitoneal wound catheters versus continuous epidural analgesia in colon and rectal surgery: a randomized controlled trial. Am J Surg 2018: 215: 570-576.

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