This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Simultaneous versus delayed resection for initially resectable synchronous colorectal cancer liver metastases. A prospective, open-label, randomized, controlled trial. Ann Surg 2021; 273: 49-56.

Published: 7th April 2021

Authors: Boudjema K, Locher C, Sabbagh C, Ortega-Deballon P, Heyd B, Bachellier P et al.

Conclusion

The analysis included 85 patients. Major complication rates were similar. After two years, disease-free and overall survival was improved in patients who had simultaneous resection (P=0.05).

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Anterior approach vs conventional hepatectomy for resection of colorectal liver metastasis. A randomized clinical trial. JAMA Surg 2021; 156: 31-40.

Authors: Rahbari NN, Birgin E, Bork U, Mehrabi A, Reißfelder C, Weitz J et al.

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Drain placement after uncomplicated hepatic resection increases severe postoperative complication rate. A Japanese multi-institutional randomized controlled trial (ND-trial). Ann Surg 2021; 273: 224-231.

Authors: Arita J, Sakamaki K, Saiura A, Konishi M, Sakamoto Y, Hashimoto M et al.

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Intention to control low central venous pressure reduced blood loss during laparoscopic hepatectomy: A double-blind randomized clinical trial. Surgery 2020; 167: 933-941.

Authors: Pan Y-X, Wang J-C, Lu X-Y , Chen J-B, He W, Chen J-C et al.

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Survival advantage of laparoscopic versus open resection for colorectal liver metastases. A meta-analysis of individual patient data from randomized trials and propensity-score matched studies. Ann Surg 2020; 272: 253-265.

Authors: Syn NL, Kabir T, Koh YY, Tan HL, Wang LZ, Chin BZ et al.

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Antimicrobial prophylaxis for 1 day versus 3 days in liver cancer surgery: a randomized controlled non-inferiority trial. Surg Today 2019; 49: 859-869

Authors: Takayama T, Aramaki O, Shibata T, Oka M, Itamoto T, Shimada M et al.

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The effect of fibrinogen/thrombin-coated collagen patch (TachoSil) application in pancreaticojejunostomy for prevention of pancreatic fistula after pancreaticoduodenectomy: a randomized clinical trial. World J Surg 2019; 43: 3128–3137

Authors: Kwon J, Shin SH, Lee S, Park G, Park Y, Lee SJ et al.

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Antibiotic irrigation during pancreatoduodenectomy to prevent infection and pancreatic fistula: a randomized controlled clinical trial. Surgery 2019; 166: 469-475

Authors: Maatman TK, Weber DJ, Timsina LR, Zyromski NJ, Koniaris LG, House MG et al.

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Laparoscopic versus open pancreaticoduodenectomy. A systematic review and meta-analysis of randomized controlled trials. Ann Surg 2020; 271: 54-66

Authors: Nickel F, Haney CM, Kowalewski KF, Probst P, Limen EF, Kalkum E et al.

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Does the artery-first approach improve the rate of R0 resection in pancreatoduodenectomy? A multicenter, randomized, controlled trial. Ann Surg 2019; 270: 738-746

Authors: Sabater L, Cugat E, Serrablo A, Suarez-Artacho G, Diez-Valladares L, Santoyo-Santoyo J et al.

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A randomized controlled trial comparing epidural analgesia versus continuous local anesthetic infiltration via abdominal wound catheter in open liver resection. Ann Surg 2019; 269: 413-419.

Authors: Bell R, Ward D, Jeffery J, Toogood G, Lodge JP, Rao K et al.

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Short-term preoperative diet decreases bleeding after partial hepatectomy. Results from a multi-institutional randomized controlled trial. Ann Surg 2019; 269: 48-52.

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Laparoscopic versus open hepatic resection for solitary hepatocellular carcinoma less than 5cm in cirrhotic patients: a randomized controlled study. J Lap Endosc Adv Surg Tech A 2018; 28: 302-310.

Authors: El-Gendi A, El-Shafei M, El-Gendi S, Shawky A