This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Antibiotic therapy for prevention of fistula in-ano after incision and drainage of simple perianal abscess: a randomized single blind clinical trial. Surgery 2017; 162: 1017-1025.

Published: 17th May 2018

Authors: Ghahramani L, Minaie MR, Arasteh P, Hosseini SV, Izadpanah A, Bananzadeh AM et al.

Conclusion

This study included 300 evaluable patients randomized to a one week course of postoperative metronidazole and ciprofloxacin or no antibiotic. The antibiotics reduced the rate of subsequent fistula at three months, P<0.001.

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