Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Antibiotic therapy versus appendectomy for acute appendicitis: a meta-analysis World J Surg 2010; 34: 199-209

Authors: Varadhan KK, Humes DJ, Neal KR, Lobo DN

Scientific Surgery

A randomized, clinical trial of frozen versus standard nasogastric tube placement. World J Surg 2009; 33: 1789-1792.

Authors: Chun DH, Kim NY, Shin YS, Kim SH.

Scientific Surgery

Effect of high perioperative oxygen fraction on surgical site infection and pulmonary complications after abdominal surgery. The PROXI randomized clinical trial. JAMA 2009; 302: 1543¿1550.

Authors: Meyhoff CS, Wetterslev J, Jorgensen LN, Henneberg SW, Hogdall C, Lundvall L et al. et al.

Scientific Surgery

A meta-analysis of randomized controlled trials assessing the prophylactic use of ceftriaxone. World J Surg 2009; 33: 2538-2550.

Authors: Woodfield JC, Beshay N, van Rij AM.

Scientific Surgery

Diathermy vs. scalpel skin incisions in general surgery: double-blind, randomized, clinical trial. World J Surg 2009; 33: 1594-1599.

Authors: Shamim M.

Scientific Surgery

Long term outcomes of laparoscopic versus open ileocolic resection for Crohn’s Disease: follow-up of a prospective randomized trial Surgery 2008; 144: 622-628

Authors: Stocchi L, Milsom JW, Fazio VW

Scientific Surgery

Randomised controlled study of branched chain amino acid-enriched total parental nutrition in malnourished patients with gastrointestinal cancer undergoing surgery. Am Surg 2008; 74: 237-242.

Authors: Sun LC, Shih YL, Lu CY, Hsieh JS, Chuang JF, Chen FM et al. et al.

Scientific Surgery

Continuous positive airway pressure for treatment of respiratory complications after abdominal surgery; a systematic review and meta-analysis. Ann Surg 2008; 247: 617-626.

Authors: Ferreyra G, Baussano I, Squadrone V, Richiardi L, Marchiaro G, Del Sorbo L et al.

Scientific Surgery

A sprayable hydrogel adhesion barrier facilitates closure of defunctioning loop ileostomy: a randomized trial. Dis Colon Rectum 2008; 51: 956-960.

Authors: Tjandra JJ, Chan MKY.

Scientific Surgery

Efficacy of probiotics in irritable bowel syndrome: a meta-analysis of randomised, controlled trials Dis Colon Rectum 2008; 51: 1775-1780

Authors: Nikfar S, Rahimi R, Rahimi F, Derakhshani S, Abdollahi M

Scientific Surgery

Prospective, double-blinded, randomized, placebo-controlled comparison of local anesthetic and nonsteroidal anti-inflammatory drugs for postoperative pain management after laparoscopic surgery. Am Surg 2007; 73: 618-624.

Authors: Newcomb W, Lincourt A, Hope W, Schmelzer T, Sing R, Kercher K et al.

Scientific Surgery

Maintenance therapy with certolizumab pegol for Crohn’s Disease. N Engl J Med 2007; 357: 239-250.

Authors: Schreiber S, Khaliq-Kareemi M, Lawrance IC, Thomsen OO, Hanauer SB, McColm J et al.

Scientific Surgery

Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforation. N Engl J Med 2006; 354: 2225¿2234.

Authors: Moss RL, Dimmitt RA, Barnhart DC, Sylvester KG, Brown RL, Powell DM et al.

Scientific Surgery

Laparoscopic versus open appendectomy in children: a meta-analysis. Ann Surg 2006; 243: 17-27.

Authors: Aziz O, Athanasiou T, Tekkis P, Purkayastha S, Haddow J, Malinovski V et al.

Scientific Surgery

Appendectomy versus antibiotic treatment in acute appendicitis. A prospective multicenter randomized controlled trial. World J Surg 2006; 30: 1033¿1037.

Authors: Styrud J, Eriksson S, Nilsson I, Ahlberg G, Haapaniemi S, Neovius G et al.

Scientific Surgery

Acute non-specific abdominal pain: a randomized, controlled trial comparing early laparoscopy versus clinical observation. Ann Surg 2006; 244: 881¿888.

Authors: Morino M, Pellegrino L, Castagna E, Farinella E, Mao P.

Scientific Surgery

Randomized clinical trial of laparoscopic versus open appendicectomy for confirmed appendicitis. Br J Surg 2005; 92: 298¿304.

Authors: Moberg A-C, Berndsen F, Palmquist I, Petersson U, Resch T, Montgomery A. et al.

Scientific Surgery

Laparoscopic versus open appendectomy: a prospective randomized double-blind study. Ann Surg 2005; 242: 439¿450.

Authors: Katkhouda N, Mason RJ, Towfigh S, Gevorgyan A, Essani R.

Scientific Surgery

Growth hormone, glutamine and an optimal diet reduces parenteral nutrition in patients with short bowel syndrome: a prospective, randomized, placebo-controlled, double-blind clinical trial. Ann Surg 2005; 242: 655-661.

Authors: Byrne TA, Wilmore DW, Iyer K, Dibaise J, Clancy K, Robinson MK et al.

Scientific Surgery

Natalizumab induction and maintenance therapy for Crohn¿s disease. N Engl J Med 2005; 353: 1912¿1925.

Authors: Sandborn WJ, Colombel JF, Enns R, Feagan BG, Hanauer SB, Lawrance IC et al.

Scientific Surgery

Randomized controlled trial of gastrograffin in adhesive small bowel obstruction. Aust NZ J Surg 2005; 75: 672-674.

Authors: Burge J, Abbas SA, Roadley G, Donald J, Connolly A, Bissett P et al. et al.

Scientific Surgery

Randomised clinical trial of synbiotic therapy in elective surgical patients. Gut 2004; 53: 241-245.

Authors: Anderson ADG, McNaught CE, Jain PK, MacFie J

Scientific Surgery

CDP571, a humanised monoclonal antibody to tumour necrosis factor alpha, for moderate to severe Crohn’s disease: a randomised, double blind, placebo controlled trial Gut 2004; 53: 1485-93.

Authors: Sandborn WJ, Feagan BG, Radford-Smith G, Kovacs A, Enns R, Innes A et al.

Scientific Surgery

Advantages of focused helical computed tomographic scanning with rectal contrast only vs. triple contrast in the diagnosis of clinically uncertain acute appendicitis Arch Surg 2004; 139: 495-500.

Authors: Mittal VK, Goliath J, Sabir M, Patel R, Richards BR, Alkalay I et al. et al.

Scientific Surgery

The efficacy of postoperative oral antibiotics in appendicitis: a randomized prospective double-blinded study. Am Surg 2004; 10: 858-862.

Authors: Taylor E, Berjis A, Bosch T, Hoehne F, Ozaeta M.

Scientific Surgery

Efficacy of pre-incisional bupivacaine infiltration on postoperative pain relief after appendectomy: prospective double-blind randomized trial. World J Surg 2004; 28: 947-950.

Authors: Lohsiriwat V, Lert-akyamanee N, Rushatamukayanunt W.

Scientific Surgery

Randomized clinical trial of the effect of interferon alpha on survival in patients with disseminated midgut carcinoid tumours. Br J Surg 2003; 90: 687-93.

Authors: Kölby L, Persson G, Franzén S, Ahrén B.

Scientific Surgery

Bioresorbable adhesion barrier facilitates early closure of the defunctioning ileostomy after rectal excision: a prospective, randomized trial. Dis Colon Rectum 2003; 46: 1200-7

Authors: Tang C-L, Seow-Choen F, Fook-Chong S, Eu K-W.

Scientific Surgery

Laparoscopic adhesiolysis in patients with chronic abdominal pain: a blinded randomised controlled multi-centre trial. Lancet 2003; 361: 1247-51.

Authors: Swank DJ, Swank-Bordewijk SC, Hop WC, van Erp WF, Janssen IM, Bonjer HJ et al et al.

Scientific Surgery

Laparoscopic versus open surgical exploration in premenopausal women with suspected acute appendicitis S Afr J Surg 2003; 41: 82-85.

Authors: Bruwer F, Coetzer M, Warren BL.

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