The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours: a multicentre, open-label, randomised controlled trial. Lancet Gastroenterol Hepatol 2021; 6: 438-447.

Published: 24th November 2021

Authors: Wang M, Li D, Chen R, Huang X, Li J, Liu Y et al.


The laparoscopic approach was safe and effective in this study that included 656 procedures. Modified intention to treat analysis suggested patients who had laparoscopic surgery had a shorter length of hospital stay (15 vs 16 days, P=0.02), but rates of morbidity and mortality up to 90 days were similar.

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