This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Randomized controlled trial of intraportal chemotherapy combined with adjuvant chemotherapy (mFOLFOX6) for stage II and III colon cancer. Ann Surg 2016; 263: 434-439.

Published: 2nd November 2016

Authors: Chang W, Wei Y, Ren L, Zhong Y, Yu Y, Chen J et al.

Conclusion

Some 237 patients were included and followed for a median of 44 months. Three year disease-free survival was improved by the addition of intraportal chemotherapy (85.2 versus 75.6 per cent, P=0.03), but there was no difference in overall survival.

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