This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Safety and efficacy of remote ischemic preconditioning in patients with severe carotid artery stenosis before carotid artery stenting. A proof-of-concept, randomized controlled trial. Circulation 2017; 135: 1325-1335.

Published: 2nd August 2017

Authors: Zhao W, Meng R, Ma C, Hou B, Jiao L, Zhu F et al.

Conclusion

A total of 189 patients were randomized to preconditioning, sham or control groups. The rate of new diffusion-weighted brain lesions on MRI after carotid stenting was lowest after preconditioning (15.9 per cent) compared to sham (36.5 per cent) and control groups (41.3 per cent); both P<0.01. Clinical adverse outcomes were rare, and equally distributed.

Pubmed Link

You may also be interested in

Scientific Surgery

Efficacy and safety of using dual versus monotherapy antiplatelet agents in secondary stroke prevention: systematic review and meta-analysis of randomized controlled clinical trials. Circulation 2021; 143: 2441–2453.

Authors: Trifan G, Gorelick PB, Testai FD

Scientific Surgery

Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy. Lancet 2021; 398: 1065-1073.

Authors: Halliday A, Bulbia R, Bonati LH, Chester J, Cradduck-Bamford A, Peto R et al.

Scientific Surgery

Network meta-analysis of carotid endarterectomy closure Techniques. Eur J Vasc Endovasc Surg 2021; 61: 181-190.

Authors: Lazarides MK, Christaina E, Argyriou C, Georgakarakos E, Tripsianis G, Georgiadis GS et al.

Scientific Surgery

Overview of primary and secondary analyses from 20 randomised controlled trials comparing carotid artery stenting with carotid endarterectomy. Eur J Vasc Endovasc Surg 2019; 58: 479-493

Authors: Batchelder AJ, Saratzis A, Naylor AR

Scientific Surgery

Overview of primary and secondary analyses from 20 randomised controlled trials comparing carotid artery stenting with carotid endarterectomy. Eur J Vasc Endovasc Surg 2019; 58: 479-493

Authors: Batchelder A, Saratzis A, Naylor AR

Scientific Surgery

Antiplatelet therapy vs anticoagulation therapy in cervical artery dissection. The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial final results. JAMA Neurol 2019; 76: 657-664.

Authors: Markus HS, Levi C, King A, Madigan J, Norris J, et al. for the et al.

Scientific Surgery

Optimal antiplatelet therapy in moderate to severe asymptomatic carotid stenosis: a comprehensive review of the literature. Eur J Vasc Endovasc Surg 2019; 57: 199-211.

Authors: Murphy SJ, Naylor AR, Ricco J-B, Sillesen H, Kakkos S, Halliday H et al.

Scientific Surgery

A meta-analysis of randomized trials comparing bovine pericardium and other patch materials for carotid endarterectomy. J Vasc Surg 2018; 68: 1241–1256.

Authors: Texakalidis P, Giannopoulos S, Charisis N, Giannopoulos S, Karasavvidis T, Koullias G et al.

Scientific Surgery

Clopidogrel plus aspirin versus aspirin alone for acute minor ischaemic stroke or high-risk transient ischaemic attack. BMJ 2018; 363: k5108.

Authors: Hao Q, Tampi M, O’Donnell M, Foroutan F, Siemieniuk RAC, Guyatt G et al.

Scientific Surgery

Safety of stenting and endarterectomy for asymptomatic carotid artery stenosis: a meta-analysis of randomised controlled trials. Eur J Vasc Endovasc Surg 2018; 55: 614-624.

Authors: Cui L, Han Y, Zhang S, Liu X, Zhang J

Scientific Surgery

Association between age and risk of stroke or death from carotid endarterectomy and carotid stenting: a meta-analysis of pooled patient data from four randomised trials. Lancet 2016; 387: 1305-1311.

Authors: Howard G, Roubin GS, Jansen O, Hendrikse J, Halliday A, Fraedrich G et al.

Scientific Surgery

Long-term results of stenting versus endarterectomy for carotid artery stenosis. N Engl J Med 2016; 374: 1021-1031.

Authors: Brott TG, Howard G, Roubin GS, Meschia JF, Mackey A, Brooks W et al.