This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Recurrence of breast cancer after regional or general anaesthesia: a randomized controlled trial. Lancet 2019; 394: 1807-1815

Published: 24th January 2020

Authors: Sessler DI, Pei L, Huang Y, Fleischmann E, Marhofer P, Kurz A et al.

Conclusion

A total of 2108 women having resectional breast surgery were randomized to GA or regional block with sedation. After median follow-up of 36 months recurrent breast cancer was reported in 10 per cent of both groups. Rates of early and late postoperative pain were also similar.

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