This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of low-intensity vs high-intensity home-based walking exercise on walk distance in patients with peripheral artery disease. The LITE Randomized Clinical Trial. JAMA 2021; 325: 1266-1276.

Published: 1st November 2021

Authors: McDermott MM, Spring B, Tian L, Treat-Jacobsen D, Ferrucci L, Lloyd-Jones D et al.

Conclusion

Some 305 patients were randomized to one of two different home exercise schedules or a control group, and followed for 12 months. The six minute walking test did not improve in the control or low intensity exercise groups, but improved by 35m on average in the high-intensity exercise group (P<0.001).

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