The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Electrospun P(LLA-CL) nanoscale fibrinogen patch vs porcine small intestine submucosa graft repair of inguinal hernia in adults: a randomized, single-blind, controlled, multicenter, noninferiority trial. J Am Coll Surg 2019; 229: 541–551

Published: 15th June 2020

Authors: Li S, Xiao S, Yang L, Hua L, Qiu Z, Hu X et al.


A total of 172 procedures were included and patients followed for 33 months. Recurrence occurred after two procedures using porcine intestinal submucosa and none after the fibrinogen patch. The rates of chronic groin pain were similar.

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