This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

An evaluation of the effect of an angiotensin-converting enzyme inhibitor on the growth rate of small abdominal aortic aneurysms: a randomized placebo-controlled trial (AARDVARK). Eur Heart J 2016; 37: 3213-3221.

Published: 17th May 2017

Authors: Bicknell CD, Kiru G, Falaschetti E, Powell JT, Poulter NR, for the et al.

Conclusion

Two hundred and twenty-four people with small and medium aneurysms were randomized to amlodipine, perindopril or placebo and followed for two years. The active medications lowered blood pressure, but had no significant effect on aneurysm growth rates.

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