The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Five-year survival outcomes of hybrid minimally invasive esophagectomy in esophageal cancer. Results of the MIRO Randomized Clinical Trial. JAMA Surg 2021; 156: 323-332.

Published: 24th November 2021

Authors: Nuytens F, Dabakuyo-Yonli TS, Meunier B, Gagnière J, Collet D, D’Journo XB et al.


Some 207 patients were followed for a median 58.2 months. The minimally invasive method had similar outcomes to open surgery: disease-free survival - hazard ratio 0.81, 95 per cent confidence interval 0.55 to 1.17; and overall survival - 0.71, 0.48 to 1.06.

Pubmed Link