This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Prospective randomized controlled trial of liberal vs. restricted perioperative fluid management in patients undergoing pancreatectomy. Ann Surg 2016; 264: 591-598.

Published: 9th November 2016

Authors: Grant F, Brennan MF, Allen PJ,, DeMatteo RP, Kingham TP, D’Angelica M et al.

Conclusion

A total of 330 patients were randomized. There were two deaths. Postoperative complication rates were similar after liberal (20 per cent) and restricted (27 per cent) regimens, P=0.6.

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