Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Effect of fecal microbiota transplantation on 8-week remission in patients with ulcerative colitis. A randomized clinical trial. JAMA 2019; 321: 156-164.

Authors: Costello SP, Hughes PA, Waters O, Bryant RB, Vincent AD, Blatchford P et al.

Scientific Surgery

Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled study. Gut 2018; 67: 2107–2115.

Authors: Halkjær SI, Christensen AH, Lo BZS, Browne PD, Günther S, Hansen LH et al.

Scientific Surgery

Tranexamic acid for lower GI hemorrhage: a randomized placebo-controlled clinical trial. Dis Colon Rectum 2018; 61: 99-106.

Authors: Smith S, Murray D, Pockney P, Bendinelli C, Draganic B, Carroll R et al.

Scientific Surgery

Telemedicine for management of inflammatory bowel disease (myIBDcoach): a pragmatic, multicentre, randomized controlled trial. Lancet 2017; 390: 959–968.

Authors: de Jong MJ, van der Meulen-de Jong AE, Romberg-Camps MJ, Becx MC, Maljaars JP, Cilissen M et al.

Scientific Surgery

Frozen vs fresh fecal microbiota transplantation and clinical resolution of diarrhea in patients with recurrent Clostridium difficile infection. A randomized clinical trial. JAMA 2016; 315: 142-149.

Authors: Lee CH, Steiner T, Petrof EO, Smieja M, Roscoe D, Nematallah A et al. et al.

Scientific Surgery

Crohn’s disease management after intestinal resection: a randomised trial. Lancet 2015; 385:1406–1417.

Authors: De Cruz P, Kamm MA, Hamilton AL, Ritchie KJ, Krejany EO, Gorelik A et al. et al.

Scientific Surgery

A prospective, randomized, non-inferiority trial of steroid dosing after major colorectal surgery. Ann Surg 2014; 259: 32-37.

Authors: Zaghiyan K, Melmed GY, Berel D, Ovsepyan G, Murrell Z, Fleshner P et al.

Scientific Surgery

A randomised phase I study of etrolizumab (rhuMab beta7) in moderate to severe ulcerative colitis. Gut 2013; 62: 1122-1130.

Authors: Rutgeerts PJ, Fedorak RN, Hommes DW, Sturm A, Baumgart DC, Bressler B et al. et al.

Scientific Surgery

Tofacitinib, an oral janus kinase inhibitor, in active ulcerative colitis. N Engl J Med 2012; 367: 616-624.

Authors: Sandborn WJ, Ghosh S, Panes J, Vranic I, Su C, Rousell S et al. et al.

Scientific Surgery

Randomized trial of laparoscopically assisted versus open colorectal resection for endometriosis: morbidity, symptoms, quality of life and fertility. Ann Surg 2010; 251: 1018-1023.

Authors: Darai E, Dubernard G, Coutant C, Frey C, Rouzier R, Ballester M. et al.

Scientific Surgery

Prospective, randomized, mulitcenter, controlled trial of a bioartificial liver in treating acute liver failure. Ann Surg 2004; 239: 660-670.

Authors: Demetriou AA, Brown RS Jr, Busuttil RW, Fair J, McGuire B, Rosenthal P et al.

Scientific Surgery

Hand-assisted laparoscopic versus open restorative proctocolectomy with ileal pouch anal anastomosis: a randomized trial. Ann Surg 2004; 240: 984-992.

Authors: Maartense S, Dunker MS, Slors JF, Cuesta MA, Gouma DJ, van Deventer SJ et al. et al.

Scientific Surgery

Randomized clinical trial to determine if delay from time of penetrating colonic injury precludes primary repair. Br J Surg 2002; 89: 993-8.

Authors: Kamwendo NY, Modiba MCM, Matlala NS, Becker PJ.

Scientific Surgery

Wound management after colon injury: open or closed? A prospective randomized trial Am Surg 2002; 68: 795-801

Authors: Velmahos GC, Vassiliu P, Demetriades D, Chan LS, Murray J, Salim A et al et al.

Scientific Surgery

Primary repair of penetrating colon injuries: a systematic review. Dis Colon Rectum 2002; 45: 1579-87

Authors: Singer MA, Nelson RL.

Scientific Surgery

A randomised trial to assess the safety and efficacy of carbon dioxide versus air insufflation in colonoscopy Gut 2002; 50: 604-7.

Authors: Bretthauer M, Thiis, Evensen E, Huppertz, Hauss G, Gisselsson L et al.

Scientific Surgery

Effect of magnetic endoscope imaging on colonoscopy performance: a randomised controlled trial. Lancet 2000; 356: 1718-22.

Authors: Shah S, Brooker JC, Williams CB, Thapar C, Saunders BP.

Scientific Surgery

Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial. Lancet 1999; 354: 635-9.

Authors: Rembacken BJ, Snelling AM, Hawkey PM, Chalmers DM, Axon ATR.

Scientific Surgery

Home rectal evacuation prior to a colorectal clinic appointment: a prospective, randomized controlled, single-blind trial. Colorectal Dis 1999; 1: 158-61.

Authors: Lobo DN, Riddick ACP, Iftikhar SY, Gudgeon AM.

Scientific Surgery

Neostigmine for the treatment of acute colonic pseudo-obstruction. N Engl J Med 1999; 341: 137-41.

Authors: Ponec RJ, Saunders MD, Kimmey MB.