This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Frozen vs fresh fecal microbiota transplantation and clinical resolution of diarrhea in patients with recurrent Clostridium difficile infection. A randomized clinical trial. JAMA 2016; 315: 142-149.

Published: 29th February 2016

Authors: Lee CH, Steiner T, Petrof EO, Smieja M, Roscoe D, Nematallah A et al. et al.

Conclusion

Some 219 patients were randomized to receive fresh or (thawed) frozen bacteria. Both were equally effective at achieving clinical resolution: per protocol results 85.1 per cent fresh versus 83.5 per cent frozen.

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Long-term outcomes of a randomized controlled trial of single-incision versus multi-port laparoscopic colectomy for colon cancer. Ann Surg 2021; 273: 1060-1065.

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Authors: Balvardi S, Pecorelli N, Castelino T, Niculiseanu P, Alhashemi M, Liberman AS et al.