This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Crohn’s disease management after intestinal resection: a randomised trial. Lancet 2015; 385:1406–1417.
Published: 23rd June 2015
Authors: De Cruz P, Kamm MA, Hamilton AL, Ritchie KJ, Krejany EO, Gorelik A et al. et al.
Conclusion
Patients were included if they had an anastomosis accessible to colonoscopy and all received 3 months of metronidazole postoperatively. Some 174 patients were randomly assigned colonoscopic or standard follow-up, with stepped-up care for local recurrence. After 18 months, endoscopic recurrence occurred in 49 per cent of patients having active care versus 67 per cent having standard care (P=0.03).
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