Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med 2013; 369: 1406-1415.

Authors: The Hokusai-VTE Investigators

Scientific Surgery

Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis. Circulation 2014; 129: 764-772.

Authors: Schulman S, Kakkar AK, Goldhaber SZ, Schellong S, Eriksson H, Mismetti P et al. et al.

Scientific Surgery

Randomized, blinded study to assess the effect of povidone iodine on the groin wound of patients undergoing primary varicose vein surgery. ANZ J Surg 2013; 83: 844-846.

Authors: Walker SR, Smith A

Scientific Surgery

Randomized clinical trial comparing endovenous laser ablation and stripping of the great saphenous vein with clinical and duplex outcome after 5 years. J Vasc Surg 2013; 58: 421–426.

Authors: Rasmussen L, Lawaetz M, Bjoern L, Blemings A, Eklof B

Scientific Surgery

Randomized clinical trial of endovenous microwave ablation combined with high ligation versus conventional surgery for varicose veins. Eur J Vasc Endovasc Surg 2013; 46: 473-479.

Authors: Yang L, Wang XP, Su WJ, Zhang Y, Wang Y

Scientific Surgery

Compression stockings after endovenous laser ablation of the great saphenous vein: a prospective randomized controlled trial. Eur J Vasc Endovasc Surg 2013; 46: 588-592.

Authors: Bakker NA, Schieven LW, Bruins RMG, van den Berg M, Hissink RJ

Scientific Surgery

The influence of patient and wound variables on healing of venous leg ulcers in a randomized controlled trial of growth-arrested allogeneic keratinocytes and fibroblasts. J Vasc Surg 2013; 58: 433–439.

Authors: Lantis JC, Marston WA, Farber A, Kirsner RS, Zhang Y, Lee TD et al. et al.

Scientific Surgery

Low molecular weight heparin for prevention of venous thromboembolism after varicose vein surgery in moderate-risk patients; a randomized controlled trial. Ann Vasc Surg 2013; 27: 940-946.

Authors: Garcia EMSN, Merino B, Taylor JH, Vizcaino I, Vaquero C

Scientific Surgery

Effectiveness of intermittent pneumatic compressionin reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial. Lancet 2013; 382: 516-524.

Authors: CLOTS (Clots in Legs Or sTockings after Stroke) Trials Collaboration

Scientific Surgery

Comparing endovenous laser ablation, foam sclerotherapy, and conventional surgery for great saphenous varicose veins. J Vasc Surg 2013; 58: 727-734.

Authors: Biemans AAM, Kockaert M, Akkersdijk GP, van den Bos RR, de Maeseneer M, Cuypers P et al. et al.

Scientific Surgery

Efficacy and safety outcomes of oral anticoagulants and antiplatelet drugs in secondary prevention of venous thromboembolism: systematic review and network meta-analysis. BMJ 2013; 347: f5133.

Authors: Castelluci LA, Cameron C, Le Gal G, Rodger MA, Coyle D, Wells PS et al. et al.

Scientific Surgery

Extended use of dabigatran, warfarin, or placebo in venous thromboembolism. N Engl J Med 2013; 368: 709–718.

Authors: Schulman S, Kearon C, Kakkar AK, Schellong S, Eriksson H, Baanstra D et al. et al.

Scientific Surgery

Apixaban for extended treatment of venous thromboembolism. N Engl J Med 2013; 368: 699–708.

Authors: Agnelli G, Buller HR, Cohen A, Curto M, Gallus AS, Johnson M et al. et al.

Scientific Surgery

Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins. Ann Surg 2013; 257: 419-426.

Authors: Samuel N, Carradice D, Wallace T, Mekako A, Hatfield J, Chetter I et al.

Scientific Surgery

Endovenous laser ablation of the great saphenous vein using a bare fibre versus a tulip fibre. Eur J Vasc Endovasc Surg 2012; 44: 587-592.

Authors: Vuylsteke ME, Thomis S, Mahieu P, Mordon S, Fourneau I

Scientific Surgery

A randomized double blind trial of upward progressive versus degressive compressive stockings in patients with moderate to severe chronic venous insufficiency. J Vasc Surg 2012; 56: 1344-1350.

Authors: Couzan S, Leizorovicz A, Laporte S, Mismetti P, Pouget J-F, Chapelle C et al. et al.

Scientific Surgery

Low-dose aspirin for preventing recurrent venous thromboembolism. N Engl J Med 2012; 367: 1979–1987.

Authors: Brighton TA, Eikelboom JW, Mann K, Biostat M, Mister R, Gallus A et al. et al.

Scientific Surgery

Spray-applied cell therapy with human allogeneic fibroblasts and keratinocytes for the treatment of chronic venous leg ulcers: a phase 2, multicentre, double-blind, randomised, placebo-controlled trial. Lancet 2012; 380: 977–985.

Authors: Kirsner RS, Marston WA, Snyder RJ, Lee TD, Cargill DI, Slade HB et al.

Scientific Surgery

Dabigatran, rivaroxaban, or apixaban versus enoxaparin for thromboprophylaxis after total hip or knee replacement: systematic review, meta-analysis, and indirect treatment comparisons. BMJ 2012; 344: e3675.

Authors: Gomez-Outes A, Terleira-Feranadez AI, Suarez-Gea ML, Vargas-Castrillon E

Scientific Surgery

A systematic review and meta-analysis of randomised controlled trials comparing endovenous ablation and surgical intervention in patients with varicose veins. Eur J Vasc Endovasc Surg 2012; 44: 214-223.

Authors: Siribumrungwong B, Noorit P, Wilasrusmee C, Attia J, Thakkinstian A

Scientific Surgery

Cost and effectiveness of laser with phlebectomies compared with foam sclerotherapy in superficial venous insufficiency. Early results of a randomised controlled trial. Eur J Vasc Endovasc Surg 2012; 43: 594-600.

Authors: Lattimer CR, Azzam M, Kalodiki E, Shawish E, Trueman P, Geroulakos G et al.

Scientific Surgery

Aspirin for preventing the recurrence of venous thromboembolism. N Engl J Med 2012; 366: 1959–1967.

Authors: Becattini C, Agnelli G, Schenone A, Elchinger S, Bucherini E, Silingardi M et al. et al.

Scientific Surgery

Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med 2012; 366: 1287–1297.

Authors: The EINSTEIN-PE investigators

Scientific Surgery

Randomized controlled trial comparing treatment outcome of two compression bandaging systems and standard care without compression in venous leg ulcers. J Vasc Surg 2012; 55: 1376-1385.

Authors: Wong IKY, Andriessen A, Lee DTF, Thompson D, Wong LY, Chao DVK et al. et al.

Scientific Surgery

Prospective randomised comparative study of visual foam sclerotherapy alone or in combination with ultrasound-guided foam sclerotherapy for treatment of superficial venous insufficiency: preliminary report. Eur J Vasc Endovasc Surg 2012; 43: 343-347.

Authors: Yamaki T, Hamahata A, Soejima K, Kono T, Nozaki M, Sakurai H. et al.

Scientific Surgery

Long-term results of a randomized controlled trial on ultrasound-guided foam sclerotherapy combined with saphenofemoral ligation vs. standard surgery for varicose veins. J Vasc Surg 2012; 55: 451-457.

Authors: Kalodiki E, Lattimer CR, Azzam M, Shawish E, Bountouroglou D, Geroulakos G. et al.

Scientific Surgery

A prospective double-blind randomized controlled trial of radiofrequency versus laser treatment of the great saphenous vein in patients with varicose veins. Ann Surg 2011; 254: 876–881.

Authors: Nordon IM, Hinchchliffe RJ, Brar R, Moxey P, Black SA, Thompson MM et al. et al.

Scientific Surgery

Thigh-length versus below-knee compression elastic stockings for prevention of the postthrombotic syndrome in patients with proximal venous thrombosis: a randomized trial. Blood 2012; 119: 1561-1565.

Authors: Prandoni P, Noventa F, Quintavalla R, Bova C, Cosmi B, Siragusa S et al. et al.

Scientific Surgery

Randomized controlled trial to investigate the impact of anticoagulation on the incidence of splenic or portal vein thrombosis after laparoscopic splenectomy. Can J Surg 2011; 54: 227–231.

Authors: Wang H, Kopac D, Brisebois R, Sample C, Shapiro AM

Scientific Surgery

A pilot study on the randomization of inferior vena cava filter placement for venous thromboembolism prophylaxis in high-risk trauma patients. J Trauma 2011: 71: 323–328.

Authors: Rajasekhar A, Lottenberg L, Lottenberg R, Feezor RJ, Armen S, Liu H et al. et al.

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