The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

The influence of patient and wound variables on healing of venous leg ulcers in a randomized controlled trial of growth-arrested allogeneic keratinocytes and fibroblasts. J Vasc Surg 2013; 58: 433–439.

Published: 30th January 2014

Authors: Lantis JC, Marston WA, Farber A, Kirsner RS, Zhang Y, Lee TD et al. et al.

Conclusion

Some 228 patients with leg ulceration were allocated to one of four different cell therapies or a control group. The main determinants of wound healing were bacterial colonisation (P<0.001), wound area (P=0.026) and duration of ulceration (P=0.004).

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