This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Spray-applied cell therapy with human allogeneic fibroblasts and keratinocytes for the treatment of chronic venous leg ulcers: a phase 2, multicentre, double-blind, randomised, placebo-controlled trial. Lancet 2012; 380: 977–985.
Published: 4th January 2013
Authors: Kirsner RS, Marston WA, Snyder RJ, Lee TD, Cargill DI, Slade HB et al.
Conclusion
A total of 205 patients completed the study: there were four active treatment groups with varying doses and schedules, and one control group. Active treatment was associated with a greater reduction in mean ulcer area after twelve weeks (P=0.045).
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