This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
2 years versus 1 year of adjuvant trastuzumab for HER2-positive breast cancer (HERA): an open-label, randomised controlled trial. Lancet 2013; 382: 1021–1028.
Published: 18th February 2014
Authors: Goldhirsch A, Gelber RD, Piccart-Gebhart MJ, de Azambuja E, Procter M, Suter TM et al. et al.
Conclusion
The study included 3105 women who were disease-free at twelve months. An extra year of trastuzumab did not improve subsequent disease-free survival after median follow-up of eight years: hazard ratio 0.99, 95 per cent confidence interval 0.85 to 1.14, P=0.86.Enter text
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