This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
5-year results of accelerated partial breast irradiation using sole interstitial multicatheter brachytherapy versus whole-breast irradiation with boost after breast-conserving surgery for low-risk invasive and in-situ carcinoma of the female breast: a randomised, phase 3, non-inferiority trial. Lancet 2016; 387: 229-238.
Published: 29th March 2016
Authors: Strnad V, Ott OJ, Hildebrandt G, Kauer-Dorner D, Knauerhause H, Major T et al on behalf of the Groupe Européen de Curiethérapie of European Society for Radiotherapy and Oncology (GEC-ESTRO) et al.
Conclusion
In this study that included 1184 women, the rate of locally recurrent breast cancer after five years was similar after brachytherapy (1.44 per cent) and whole breast radiotherapy (0.92 per cent, P=0.42). Adverse side effect rates were also similar.
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