This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Axillary dissection versus no axillary dissection in older patients with T1N0 breast cancer: 15-year results of a randomized controlled trial. Ann Surg 2012; 256: 920-924.

Published: 2nd April 2013

Authors: Martelli G, Boracchi P, Ardoino I, Lozza L, Bohm S, Vetrella G et al. et al.

Conclusion

Some 238 patients with clinically node negative breast cancer were included. Disease-free and overall survival rates were similar. Only 6 per cent of patients in the control arm developed axillary recurrence.

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West German Study Plan B Trial: adjuvant four cycles of epirubicin and cyclophosphamide plus docetaxel versus six cycles of docetaxel and cyclophosphamide in HER2-negative early breast cancer. J Clin Oncol 2019; 37: 799-808

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