This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Combined screening with ultrasound and mammography vs. mammography alone in women at elevated risk of breast cancer. JAMA 2008; 299: 2151-2163.
Published: 1st January 2008
Authors: Berg W, Blume JD, Cormack JB, Mendelson EB, Lehrer D, Bohm-Velez M et al. et al.
Conclusion
Almost 3000 women with dense breast tissue in at least one quadrant on mammography were included. The addition of ultrasound detected 4.2 extra cancers per 1000 women screened (95 per cent confidence interval 1.1 to 7.2, P=0.003), but at the cost of an increased number of false positive diagnoses.
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