The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study. Gut 2020; 69: 859–867.

Published: 15th October 2020

Authors: El-Salhy M, Hatlebakk JG, Gilja OH, Kristoffersen AB, Hausken T

Conclusion

Some 165 patients were randomized to a placebo, or one of two groups with different amounts of microbiota. A 50-point reduction in IBS score was recorded in 23.6 per cent of controls, versus 76.9 per cent in patients who had 30g microbiota and 89.1 per cent who had 60g (both P<0.001).

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