This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Sequential versus triple therapy for the first-line treatment of Helicobacter pylori: a multicentre, open-label, randomised trial. Lancet 2012; 381: 205–213.

Published: 9th May 2013

Authors: Liou JM, Chen CC, Chen MJ, Chen CC, Chang CY, Fang YJ et al. et al.

Conclusion

Nine hundred patients were included in this study of three regimens. The highest eradication rate (90.7 per cent) was with lansoprazole with amoxicillin for seven days followed by lansoprazole clarithromycin and metronidazole for seven days.

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Short-term outcomes of robotic gastrectomy vs laparoscopic gastrectomy for patients with gastric cancer. A randomized clinical trial. JAMA Surg 2021; 156: 954-963.

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A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis. Results of the COMMA Trial. Ann Surg 2021; 274: 240-247.

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Authors: Lu J, Zheng C-H, Xu B-B, Xie J-W, Wang J-B, Lin J-X et al.