This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Multinational, double-blind, randomised, placebo controlled, prospective study of esomeprazole in the prevention of recurrent peptic ulcer in low-dose acetylsalicylic acid users: the LAVENDER study. Gut 2014; 63: 1061-1068.

Published: 13th November 2014

Authors: Sugano K, Choi M-G, Lin J-T, Goto S, Okada Y, Kinoshita Y et al. et al.

Conclusion

Some 364 patients with a history of peptic ulcer, and taking aspirin for cardioprotection were included. Esomeprazole improved the rate of freedom from re-ulceration at 48 weeks from 81.2 to 98.3 per cent.

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