This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Exemestane versus anastrozole in postmenopausal women with early breast cancer. NCIC CTG MA 27. A randomized controlled phase III trial. J Clin Oncol 2013; 31: 1398-1404.

Published: 30th July 2013

Authors: Goss PE, Ingle JN, Pritchard KI, Ellis MJ, Sledge GW, Budd GT et al. et al.

Conclusion

A total of 7576 women were enrolled in the study and followed for a median of 4.1 years. Four-year event-free survival rates were 91 per cent for exemestane and 91.2 per cent for anastrozole (hazard ratio 1.02, 95 per cent confidence interval 0.87 to 1.18). There were no observed differences between the drugs.

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