This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
German adjuvant intergroup node-positive study: a phase III trial to compare oral ibandronate versus observation in patients with high-risk early breast cancer. J Clin Oncol 2013; 31: 3531–3539.
Published: 18th February 2014
Authors: von Minckwitz G, Mobus V, Schneeweiss A, Huober J, Thomssen C, Untch M et al. et al.
Conclusion
This study included 3023 women. The addition of ibandronate to standard chemotherapy did not improve disease-free (hazard ratio 0.94, 95 per cent confidence interval 0.77 to 1.16) or overall survival (1.04, 0.76 to 1.42).
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