This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial. Lancet 1998; 352: 98-101.
Published: 1st January 1998
Authors: Powles T, Eeles R, Ashley S, Easton D, Chang J, Dowsett M et al. et al.
Conclusion
Some 2494 healthy women with a family history were randomized. After a median follow-up of 70 months the frequency of breast cancer was similar: tamoxifen 34, placebo 36: relative risk 1.06.
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