This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Interim cosmetic and toxicity results from RAPID: a randomized trial of accelerated partial breast irradiation using three-dimensional conformal external beam radiation therapy. J Clin Oncol 2013; 31: 4038-4046.
Published: 15th May 2014
Authors: Olivotto IA, Whelan TJ, Parpia S, Kim D-H, Berrang T, Truong PT et al. et al.
Conclusion
Some 2135 women were enrolled in this study after breast-conserving surgery. After median follow-up of 36 months, accelerated radiotherapy increased the risk of adverse cosmetic outcomes as assessed by specialist nurses (29 versus 17 per cent; P<0.001) and toxicity (P<0.001).
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