This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Long-term clinical and cost-effectiveness of early endovenous ablation in venous ulceration. A randomized clinical trial. JAMA Surg 2020; 155: 1113-1121.

Published: 7th May 2021

Authors: Gohel M, Mora J, Szigeti M, Epstein DM, Heatley F, Bradbury A et al.

Conclusion

This study included 450 participants with at least 3 years of follow-up. In the early treatment group, there was a lower rate of ulcer recurrence (incidence rate ratio 0.658, 95 per cent confidence interval 0.48 to 0.898, P=0.003), and the intervention was 91.6 per cent likely to be cost effective at the willingness to pay threshold of £20,000.

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