This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Larval therapy for leg ulcers (VenUS II): randomised controlled trial BMJ 2009; 338: 1047-1057
Published: 1st January 2009
Authors: Dumville JC, Worthy G, Bland JM, Cullum N, Dowson C, Iglesias C et al et al.
Conclusion
Some 267 patients were randomized to loose larvae, bagged larvae or standard hydrogel desloughing dressings. There was no difference between the two larval dressings. Time to ulcer healing was similar after larvae vs. hydrogel dressings: hazard ratio 1.13, 95 per cent confidence interval 0.76 to 1.68. Larvae did not improve ulcer pain, help eradicate MRSA or improve quality of life
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