This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Randomized controlled trial of intensity-modulated radiotherapy for early breast cancer: 5-year results confirm superior overall cosmesis. J Clin Oncol 2013; 31: 4488-4495.

Published: 15th May 2014

Authors: Mukesh MB, Barnett GC, Wilkinson JS, Moody AM, Wilson C, Dorling L et al. et al.

Conclusion

This study included 815 patients treated either with standard radiotherapy or simple intensity-modulated radiotherapy. After five years, fewer patients who had the novel treatment had suboptimal overall cosmesis (odds ratio 0.68, 95 per cent confidence interval 0.48 to 0.96, P=0.027) and telangiectasia (0.58, 0.36 to 0.92, P=0.021).

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