This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
RTOG 9804: A prospective randomized trial for good-risk ductal carcinoma in situ comparing radiotherapy with observation. J Clin Oncol 2015; 33: 723-731.
Published: 27th August 2015
Authors: McCormick B, Winter K, Hudis C, Kuerer HM, Rakovitch E, Smith BL et al. et al.
Conclusion
The trial closed early after 630 patients had been randomized, due to low recruitment. After seven years, ipsilateral recurrence was 0.9 per cent after radiotherapy compared to 6.7 per cent in the observation only arm, P<0.001.
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