This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Sector resection with or without postoperative radiotherapy for stage I breast cancer: 20-year results of a randomized trial. J Clin Oncol 2014; 32: 791-797.

Published: 15th May 2014

Authors: Wickberg A, Holmberg L, Adami H-O, Magnuson A, Villman K, Liljegren G et al.

Conclusion

Survival rates after 20 years were similar with, or without radiotherapy in this study that included 381 women. Cumulative probability of first breast cancer event after treatment was lower after radiotherapy (30.9 per cent) than no radiotherapy (45.1 per cent): hazard ratio 0.58, 95 per cent confidence interval 0.41 to 0.82. Most of the benefit occurred in the first five years after treatment.

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