This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

SWOG S0221: A phase III trial comparing chemotherapy schedules in high-risk early-stage breast cancer. J Clin Oncol 2015; 33: 58-64.

Published: 27th August 2015

Authors: Budd GT, Barlow WE, Moore HCF, Hobday TJ, Stewart JA, Isaacs C et al. et al.

Conclusion

This 2x2 factorial design trial tested a number of different regimens in 3250 women. Disease-free survival was similar between the regimens, and for one- and two-weekly cycles.

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