This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial. Lancet 2010; 376: 1074-1084.

Published: 2nd February 2011

Authors: Halliday A, Harrison M, Hayter E, Kong X, Mansfield A, Marro J et al. et al.

Conclusion

This study originally included 3120 patients. After ten years, the risk of stroke (including the perioperative event rate of 3 per cent) was 13.4 per cent after surgery vs. 17.9 per cent in controls: net gain 4.6 per cent.

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