The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A meta-analysis of outcomes following use of somatostatin and its analogues for the management of enterocutaneous fistulas. Ann Surg 2012; 256: 946–954.

Published: 4th March 2013

Authors: Rahbour GB, Siddiqui MR, Ullah MR, Gabe SM, Warusavitarne JB, Vaizey CJ et al.

Conclusion

Somatostatin analogues did not affect postoperative mortality in this analysis of nine randomized trials.  Both somatostatin and octreotide increased the number of pancreatic fistulas that healed (P=0.002), and also speeded up their closure (P<0.0001).

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