The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

A randomized double blind, multicentre clinical trial comparing the efficacy of calcium dobesilate with placebo in the treatment of chronic venous disease. Eur J Vasc Endovasc Surg 2008; 35: 358-365.

Published: 1st January 2008

Authors: Martinez-Zapata MJ, Moreno RM, Gich I, Urrutia G, Bonfill X.

Conclusion

Twice daily treatment for three months had no effect on the symptoms of chronic venous insufficiency, or on quality of life after three months in this trial that included 509 patients: mean CIVIQ scores 37.8 vs. 38.2 in the placebo group (P=0.07)



 

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