This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Adaptive randomization of Neratinib in early breast cancer. N Engl J Med 2016; 375: 11-22.
Published: 25th August 2016
Authors: Park JW, Liu MC, Yee D, Yau C, van’t Veer LJ, Symmans F et al.
Conclusion
This complex trial involved matching experimental neoadjuvant chemotherapy regimens with breast cancer subtypes. Some 193 women were randomized. Pathological complete response was improved in the neratinib group: 56 per cent compared to 33 per cent with control treatment.
Pubmed LinkYou may also be interested in
Scientific Surgery
Authors: Gnant M, Fitzal F, Rinnerthaler G, Steger GS, Greil-Ressler S, Balic M et al.
Scientific Surgery
Authors: Tutt ANJ, Garber JE, Kaufman B, Viale G, Fumagalli D, Rastogi P et al.
Scientific Surgery
Authors: Wang X, Wang S-S, Huang H, Cai L, Peng R-J, Lin Y et al.
Scientific Surgery
Authors: Mittendorf EA, Zhang H, Barrios CH, Saji S, Jung KH, Hegg R et al.
Scientific Surgery
Authors: Papakonstantinou A, Matikas A, Bengtsson NO, Malmstrom P, Hedayati E, Steger G et al.
Scientific Surgery
Authors: Gralow JR, Barlow WE, Paterson AHG, M’iao JL, Lew DL, Stopeck AT et al.
Scientific Surgery
Authors: Brunt AM, Haviland JS, Wheatley DA, Sydenham MA, Alhasso A, Bloomfield DJ et al.
Scientific Surgery
Authors: Su Y, Huang J, Wang S, Unger JM, Arias-Fuenzalida J, Shi Y et al.
Scientific Surgery
Authors: Yu K-D, Wu S-Y, Liu G-Y, Wu J, Di G-H, Hu Z et al.
Scientific Surgery
Authors: Nitz M, Gluz O, Clemens M, Malter W, Reimer T, Nuding B et al.
Scientific Surgery
Authors: Schmid P, Cortes J, Pusztai L, McArthur H, Kummel S, Bergh J et al.
Scientific Surgery
Authors: Whelan TJ, Julian JA, Berrang TS, Kim D-H, Germain I, Nichol AM et al.