This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01). Lancet 2016; 388: 248–25716.
Published: 25th August 2016
Authors: Uesaka K, Boku N, Kukutomi A, Okamura Y, Knoishi M, Matsumoto I et al.
Conclusion
Adjuvant chemotherapy with gemcitabine improved overall survival at five years in this study that included 385 patients from 24.4 to 44.1 percent: hazard ratio of mortality 0.57, 95 per cent confidence interval 0.44 to 0.72, P<0.0001.
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