The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Open-label, multicentre, randomized phase III trial of adjuvant chemoradiation plus interferon alfa-2b versus fluorouracil and folinic acid for patients with resected pancreatic adenocarcinoma. J Clin Oncol 2012; 30: 4077–4083.

Published: 4th March 2013

Authors: Schmidt J, Abel U, Debus J, Harig S, Hoffman K, Herrmann T et al. et al.

Conclusion

The addition of postoperative radiotherapy and interferon did not improve overall median survival in this trial that included 132 patients: 26.5 months versus 28.5 months after standard chemotherapy (P=0.99).

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