This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Antibiotic prophylaxis for the prevention of infection after major limb amputation Eur J Vasc Endovasc Surg 2009; 37: 696-703

Published: 1st January 2009

Authors: McIntosh J, Earnshaw JJ

Conclusion

The seven randomized trials were largely historical. Yet, they all showed that prophylactic antibiotics reduced the rate of amputation stump infection, and in one study the rate of re-amputation was similarly reduced

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