This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Comparative efficacy and safety of adjuvant letrozole versus anastrozole in postmenopausal patients with hormone-receptor positive, node-negative early breast cancer: final results of the randomized phase III Femara versus Anastrozole Clinical Evaluation (FACE) trial. J Clin Oncol 2017; 35: 1041-1048.

Published: 28th November 2017

Authors: Smith I, Yardley D, Burris H, De Boer R, Amadori D, McIntyre K et al.

Conclusion

Some 4136 women were included. At five years, both disease-free survival (84.9 per cent for letrozole and 82.9 per cent for anastrozole) and overall survival (89.9 and 89.2, respectively) were similar.

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