The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open label, phase 3 trial. Lancet Oncol 2021; 22: 256-266.

Published: 7th May 2021

Authors: Quenet F, Elias D, Roca L, Goere D, Ghouti L, Pocard M et al.

Conclusion

The addition of intraperitoneal chemotherapy did not improve median survival over cytoreductive surgery alone in this study that included 265 patients (41.7 versus 41.2 months respectively), but increased the risk of late complications.

Pubmed Link

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