This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Preoperative hepatic and regional arterial chemotherapy in patients who underwent curative colorectal cancer resection. A prospective, multi-center, randomized controlled trial. Ann Surg 2021; 273: 1066-1075.
Published: 4th November 2021
Authors: Zhu D, Xia J, Gu Y, Lin J, Ding K, Zhou B et al.
Conclusion
In this study that included 688 patients, the addition of regional arterial chemotherapy to standard adjuvant treatment improved five year disease-free survival (hazard ratio 0.61, 95 per cent confidence interval 0.46 to 0.81, P<0.001) and overall survival (0.61, 0.43 to 0.86, P=0.005).
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