This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of celecoxib vs placebo added to standard adjuvant therapy on disease-free survival among patients with stage III colon cancer. The CALGB/SWOG 80702 (Alliance) randomized clinical trial. JAMA 2021; 325: 1277-1286.

Published: 1st July 2021

Authors: Meyerhardt JA, Shi Q, Fuchs CS, Meyer J, Niedzwiecki D, Zemla T et al.

Conclusion

In this trial that included 2526 patients, the addition of celecoxib for three years to standard treatment did not improve disease-free survival: 76.3 versus 73.4 per cent, hazard ratio for disease recurrence or death 0.89.

Pubmed Link

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