This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Cytosponge-trefoil factor 3 versus usual care to identify Barrett’s oesophagus in a primary care setting: a multicentre, pragmatic, randomised controlled trial. Lancet 2020; 396: 333-344.

Published: 16th September 2020

Authors: Fitzgerald RC, di Pietro M, O’Donovan M, Maroni R, Muldrew B, Debiram-Beeecham I et al.

Conclusion

People over 50 with symptoms of gastro-oesophageal reflux for at least six months were included. Some 39 per cent of those offered the sponge procedure accepted it. In the next 12 months, Barrett’s was diagnosed in 140/6834 of those offered the sponge, compared to 13/6388 in the usual care group.

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