This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Effect of cognitive prehabilitation on the incidence of postoperative delirium among older adults undergoing major noncardiac surgery. The Neurobics randomized clinical trial. JAMA Surg 2021; 156: 148-156.

Published: 4th November 2021

Authors: Humeidan ML, Reyes J-PC, Mavarez-Martinez A, Roeth C, Nguyen CM, Sheridan C et al.

Conclusion

In this study that included 268 patients, preoperative tablet-based cognition exercises reduced the rate of delirium from 23 to 13.2 per cent, P=0.04.

Pubmed Link

You may also be interested in

Scientific Surgery

Incisional surgical site infections after mass and layered closure of upper abdominal transverse incisions. First results of a randomized controlled trial. Ann Surg 2021; 274: 690-697.

Authors: Grąt M, Morawski M, Krasnodębski M, Borkowski J, Krawczyk P, Grąt K et al.

Scientific Surgery

Dexamethasone and surgical-site infection. N Engl J Med 2021; 384: 1731-1741.

Authors: Corcoran TB, Myles PS, Forbes AB, Cheng AC, Bach LA, O’Loughlin E et al.

Scientific Surgery

Negative pressure wound therapy vs conventional wound treatment in subcutaneous abdominal wound healing impairment. The SAWHI randomized clinical trial. JAMA Surg 2020; 155: 469-478.

Authors: Seidel D, Diedrich S, Herrle F, Thielemann H, Marusch F, Schirren R et al.

Scientific Surgery

A single preoperative dose of tranexamic acid reduces perioperative blood loss. A meta-analysis. Ann Surg 2021; 273: 75-81.

Authors: Heyns M, Knight P, Steve AK, Yeung JK

Scientific Surgery

Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT): a randomised, double-blind, controlled trial. Lancet 2020; 396: 1353-1361.

Authors: Richards T, Baikady RR, Clevenger B, Butcher A, Abeysiri S, Chau M et al.

Scientific Surgery

Reduction of postoperative wound infections by antiseptica (RECIPE)? A Randomized Controlled Trial. Ann Surg 2020; 272: 55-64.

Authors: Strobel R, Leonhardt M, Krochmann A, Neumann K, Speichinger F, Hartmann L et al.

Scientific Surgery

Critical appraisal on the impact of preoperative rehabilitation and outcomes after major abdominal and cardiothoracic surgery: a systematic review and meta-analysis. Surgery 2020; 167: 540-549.

Authors: Kamarajah SK, Bundred J, Weblin J, Tan BHL

Scientific Surgery

Perioperative probiotics or synbiotics in adults undergoing elective abdominal surgery. A systematic review and meta-analysis of randomized controlled trials. Ann Surg 2020; 271: 1036-1047.

Authors: Chowdhury A, Adiamah A, Kushairi A, Varadhan KK, Krznaric Z, Kulkarni A et al.

Scientific Surgery

Randomized trial of perioperative probiotics among patients undergoing major abdominal operation. J Am Coll Surg 2019; 229: 533–540

Authors: Franko J, Raman S, Krishnan N, Frankova D, Tee MC, Brahmbhatt R et al.

Scientific Surgery

Preventive effects of a synthetic absorbable antiadhesive film (Seprafilm) on small bowel obstruction in patients who underwent elective surgery for colon cancer: a randomized controlled trial. J Surg Oncol 2019; 120: 1038-1043

Authors: Saito G, Sadahiro S, Ogimi T, Miyakita H, Okada K, Tanaka A et al.

Scientific Surgery

Prophylactic negative pressure wound therapy for closed laparotomy incisions. A meta-analysis of randomized controlled trials. Ann Surg 2020; 271: 67-74

Authors: Kuper TM, Murphy PB, Kaur B, Ott MC

Scientific Surgery

A systematic review and meta-analysis of remote ischemic preconditioning for vascular surgery. J Vasc Surg 2019; 70: 1353-1363

Authors: Stather PW, Wych J, Boyle JR